MSI Seminar & Workshop: Statistical methods for the exploration and the integration of biological datasets

  • IDEX UCAJedi
  • Training
  • Research
Published on September 30, 2021 Updated on October 4, 2021
Dates

on the December 9, 2021

On December 9, 2021
From 10:00 to 12:00: Seminar
From 13:30 to 16:30
: Workshop

Location
In-person seminar and workshop: INRAe Sophia-Antipolis, Route des Chappes 06560
Online attendance via Zoom is also possible

Seminar and Workshop held by Sébastien Déjean (Research Engineer at Institut de Mathématiques, Université Paul Sabatier, Toulouse)

Speaker

Sébastien Déjean, Professor at Génopole Toulouse Midi-Pyrénées
 

Abstract

It is generally admitted that single 'omics analysis does not provide enough information to give a deep understanding of a biological system, but we can obtain a more holistic view of a system by combining multiple 'omics analyses. In this context, this talk will present the mixOmics R package that proposes multivariate statistical methods to explore and integrate 'omics data sets.

The methods presented are multivariate linear methods based on the same principle as Principal Component Analysis (PCA). So, first, the talk will set the basics of multivariate linear methods through PCA. After that, the extension to discriminant (PLS-DA) and integrative (PLS, multi-block PLS) methods will be straightforward, and a specific attention will be paid to variable selection and visualization.
For the workshop, an R script enabling to reproduce some exploratory and integrative analyses on datasets included in the package will be provided to the attendees. More advanced users can bring their own data.
 

Registration

To join the seminar and the workshop (in-person or virtually), please register on https://msi.univ-cotedazur.eu/seminars/.
Should you need further information, send an email to silvia.bottini@univ-cotedazur.fr.